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Blood pressure is known to increase and blood clots in blood vessels disrupting the blood flow causing damage to the heart muscle leading to heart attacks. It is a common side effect of many medications, as well as some prescription pain medications. If it does cause side effects, it may be treated by a medication that can block pain receptors or block the receptors that can cause some of the side effects. Medications that block pain receptors are called narcotic medications or are controlled substances. Examples include painkillers. Related Article: